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Shirah, B., Overbey, E. G., Foox, J., Hirschberg, J. W., Kim, J., Ryon, K., Proszynski, J., Meydan, C., Najjar, D., Collier, P., LeRoy, E., Pandya, S., Gonzalez, Y., Persad, A. H., Ahmed, M. M., Bukhari, H., Naseer, M. I., Ashemimry, M. N., Taylor, L., . . . Mason, C. E. (2025). Telomere length dynamics associated with short-duration human spaceflight. Neuroscience Research in Short-Duration Human Spaceflight, 125-143. https://doi.org/10.1016/B978-0-443-33918-9.00003-1

Shirah, B., Zu Eulenburg, P., Overbey, E. G., Kim, J., Burke, M., Hirschberg, J. W., Schulze, I., Ryon, K., Proszynski, J., Meydan, C., Najjar, D., Foox, J., Collier, P., Nelson, T. M., Zhang, D. J., Iyoha, N. M., Jones, C. J., Przywozny, B., Sibilly, T., . . . Mason, C. E. (2025). Surrogate assessment of brain health using longitudinal measures of blood-based biomarkers in short-duration human spaceflight. Neuroscience Research in Short-Duration Human Spaceflight, 101-124. https://doi.org/10.1016/B978-0-443-33918-9.00007-9

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Jones, C. W., Overbey, E. G., Lacombe, J., Ecker, A. J., Meydan, C., Ryon, K., Tierney, B., Damle, N., MacKay, M., Afshin, E. E., Foox, J., Park, J., Nelson, T. M., Suhail Mohamad, M., Byhaqui, S. G., Aslam, B., Tali, U. A., Nisa, L., Menon, P. V., . . . Mason, C. E. (2024). Molecular and physiological changes in the SpaceX Inspiration4 civilian crew. Nature, 632(8027), 1155-1164. https://doi.org/10.1038/s41586-024-07648-x

 

Overbey, E. G., Kim, J., Tierney, B. T., Park, J., Houerbi, N., Lucaci, A. G., Garcia Medina, S., Damle, N., Najjar, D., Grigorev, K., Afshin, E. E., Ryon, K. A., Sienkiewicz, K., Patras, L., Klotz, R., Ortiz, V., MacKay, M., Schweickart, A., Chin, C. R., . . . Mason, C. E. (2024). The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. Nature, 632(8027), 1145-1154. https://doi.org/10.1038/s41586-024-07639-y

 

Mason, C. E., Green, J., Adamopoulos, K. I., Afshin, E. E., Baechle, J. J., Basner, M., Bailey, S. M., Bielski, L., Borg, J., Borg, J., Broddrick, J. T., Burke, M., Caicedo, A., Castañeda, V., Chatterjee, S., Chin, C. R., Church, G., Costes, S. V., De Vlaminck, I., . . . Overbey E. G.,. . . Beheshti, A. (2024). A second space age spanning omics, platforms and medicine across orbits. Nature, 632(8027), 995-1008. https://doi.org/10.1038/s41586-024-07586-8 

 

Rutter, L. A., MacKay, M. J., Cope, H., Szewczyk, N. J., Kim, J., Overbey, E. G., Tierney, B. T., Muratani, M., Lamm, B., Bezdan, D., Paul, A. M., Schmidt, M. A., Church, G. M., Giacomello, S., & Mason, C. E. (2024). Protective alleles and precision healthcare in crewed spaceflight. Nature Communications, 15(1), 1-13. https://doi.org/10.1038/s41467-024-49423-6 

 

Tierney, B. T., Kim, J., Overbey, E. G., Ryon, K. A., Foox, J., Sierra, M. A., Bhattacharya, C., Damle, N., Najjar, D., Park, J., Garcia Medina, J. S., Houerbi, N., Meydan, C., Wain Hirschberg, J., Qiu, J., Kleinman, A. S., A., G., MacKay, M., Afshin, E. E., . . . Mason, C. E. (2024). Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight. Nature Microbiology, 9(7), 1661-1675. https://doi.org/10.1038/s41564-024-01635-8 

 

Cope, H., Elsborg, J., Demharter, S., McDonald, J. T., Wernecke, C., Parthasarathy, H., Unadkat, H., Chatrathi, M., Claudio, J., Reinsch, S., Avci, P., Zwart, S. R., Smith, S. M., Heer, M., Muratani, M., Meydan, C., Overbey, E. G., Kim, J., Chin, C. R., . . . Beheshti, A. (2024). Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology. Communications Medicine, 4(1), 1-18. https://doi.org/10.1038/s43856-024-00532-9 

 

Kim, J., Tierney, B. T., Overbey, E. G., Dantas, E., Fuentealba, M., Park, J., Narayanan, S. A., Wu, F., Najjar, D., Chin, C. R., Meydan, C., Loy, C., Mathyk, B., Klotz, R., Ortiz, V., Nguyen, K., Ryon, K. A., Damle, N., Houerbi, N., . . . Mason, C. E. (2024). Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight. Nature Communications, 15(1), 1-18. https://doi.org/10.1038/s41467-024-49211-2

 

Houerbi, N., Kim, J., Overbey, E. G., Batra, R., Schweickart, A., Patras, L., Lucotti, S., Ryon, K. A., Najjar, D., Meydan, C., Damle, N., Chin, C., Narayanan, S. A., Guarnieri, J. W., Widjaja, G., Beheshti, A., Tobias, G., Vatter, F., Hirschberg, J. W., . . . Mason, C. E. (2024). Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight. Nature Communications, 15(1), 1-17. https://doi.org/10.1038/s41467-024-48841-w

 

Grigorev, K., Nelson, T. M., Overbey, E. G., Houerbi, N., Kim, J., Najjar, D., Damle, N., Afshin, E. E., Ryon, K. A., Melnick, A. M., Mateus, J., & Mason, C. E. (2024). Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses. Nature Communications, 15(1), 1-11. https://doi.org/10.1038/s41467-024-48929-3

 

Wu, F., Du, H., Overbey, E. G., Kim, J., Makhijani, P., Martin, N., Lerner, C. A., Nguyen, K., Baechle, J., Valentino, T. R., Fuentealba, M., Bartleson, J. M., Halaweh, H., Winer, S., Meydan, C., Sayed, N., Melov, S., Muratani, M., Gerencser, A. A., . . . Winer, D. A. (2024). Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight. Nature Communications, 15(1), 1-22. https://doi.org/10.1038/s41467-023-42013-y

 

M., T., Maranon, D. G., Nelson, C. B., Lewis, A. M., Luxton, J. J., Taylor, L. E., Altina, N., Wu, F., Du, H., Kim, J., Damle, N., Overbey, E. G., Meydan, C., Grigorev, K., Winer, D. A., Furman, D., Mason, C. E., & Bailey, S. M. (2024). Telomeric RNA (TERRA) increases in response to spaceflight and high-altitude climbing. Communications Biology, 7(1), 1-12. https://doi.org/10.1038/s42003-024-06014-x

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McDonald, J. T., Kim, J., Farmerie, L., Johnson, M. L., Trovao, N. S., Arif, S., Siew, K., Tsoy, S., Bram, Y., Park, J., Overbey, E. G., Ryon, K., Haltom, J., Singh, U., Enguita, F. J., Zaksas, V., Guarnieri, J. W., Topper, M., Wallace, D. C., . . . Beheshti, A. (2024). Space radiation damage rescued by inhibition of key spaceflight associated miRNAs. Nature Communications, 15(1), 1-23. https://doi.org/10.1038/s41467-024-48920-y

 

Park, J., Overbey, E. G., Narayanan, S. A., Kim, J., Tierney, B. T., Damle, N., Najjar, D., Ryon, K. A., Proszynski, J., Kleinman, A., Hirschberg, J. W., MacKay, M., Afshin, E. E., Granstein, R., Gurvitch, J., Hudson, B. M., Rininger, A., Mullane, S., Church, S. E., . . . Mason, C. E. (2024). Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight. Nature Communications, 15(1), 1-14. https://doi.org/10.1038/s41467-024-48625-2

 

Siew, K., Nestler, K. A., Nelson, C., Zhong, C., Li, Z., Grillo, A., Wan, E. R., Patel, V., Overbey, E. G., Kim, J., Yun, S., Vaughan, M. B., Cheshire, C., Cubitt, L., Yousef, M., Boyko, V., Meydan, C., Barker, P., Arif, S., . . . Walsh, S. B. (2024). Cosmic kidney disease: An integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction. Nature Communications, 15(1), 1-20. https://doi.org/10.1038/s41467-024-49212-1

 

Mathyk, B. A., Tabetah, M., Karim, R., Zaksas, V., Kim, J., Anu, R. I., Muratani, M., Tasoula, A., Singh, R. S., Chen, Y., Overbey, E. G., Park, J., Cope, H., Fazelinia, H., Povero, D., Borg, J., Klotz, R. V., Yu, M., Young, S. L., . . . Beheshti, A. (2024). Spaceflight induces changes in gene expression profiles linked to insulin and estrogen. Communications Biology, 7(1), 1-17. https://doi.org/10.1038/s42003-023-05213-2

 

Borg, J., Loy, C., Kim, J., Buhagiar, A., Chin, C., Damle, N., De Vlaminck, I., Felice, A., Liu, T., Matei, I., Meydan, C., Muratani, M., Mzava, O., Overbey, E. G., Ryon, K. A., Smith, S. M., Tierney, B. T., Trudel, G., Zwart, S. R., . . . Borg, J. (2024). Spatiotemporal expression and control of haemoglobin in space. Nature Communications, 15(1), 1-15. https://doi.org/10.1038/s41467-024-49289-8

 

Overbey, E. G., Ryon, K., Kim, J., Tierney, B. T., Klotz, R., Ortiz, V., Mullane, S., Schmidt, J. C., MacKay, M., Damle, N., Najjar, D., Matei, I., Patras, L., Garcia Medina, J. S., Kleinman, A. S., Wain Hirschberg, J., Proszynski, J., Narayanan, S. A., Schmidt, C. M., . . . Mason, C. E. (2024). Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA). Nature Communications, 15(1), 1-14. https://doi.org/10.1038/s41467-024-48806-z

 

Camera, A., Tabetah, M., Castañeda, V., Kim, J., Galsinh, A. S., Salinas, I., Seylani, A., Arif, S., Das, S., Mori, M. A., Carano, A., De Oliveira, L. C., Muratani, M., Barker, R., Zaksas, V., Goel, C., Dimokidis, E., Taylor, D. M., Jeong, J., Overbey E. G., . . . Beheshti, A. (2024). Aging and putative frailty biomarkers are altered by spaceflight. Scientific Reports, 14(1), 1-21. https://doi.org/10.1038/s41598-024-57948-5

 

Sanders, L. M., Grigorev, K. A., Scott, R. T., M., A., Polo, S., Gilbert, R., Overbey, E. G., Kim, J., Mason, C. E., & Costes, S. V. (2024). Inspiration4 data access through the NASA Open Science Data Repository. Npj Microgravity, 10(1), 1-7. https://doi.org/10.1038/s41526-024-00393-5

 

Sebastian, J., Sienkiewicz, K., Narayanan, S. A., Overbey, E. G., Grigorev, K., Ryon, K. A., Burke, M., Proszynski, J., Tierney, B., Schmidt, C. M., Klotz, R., Ortiz, V., Foox, J., Chin, C., Najjar, D., Matei, I., Chan, I., Cruchaga, C., Kleinman, A., . . . Mason, C. E. (2024). Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight. Precision Clinical Medicine, 7(1). https://doi.org/10.1093/pcmedi/pbae007

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​Overbey, E. G., Das, S., Cope, H., Madrigal, P., Andrusivova, Z., Frapard, S., Klotz, R., Bezdan, D., Gupta, A., Scott, R. T., Park, J., Chirko, D., Galazka, J. M., Costes, S. V., Mason, C. E., Herranz, R., Szewczyk, N. J., Borg, J., & Giacomello, S. (2022). Challenges and considerations for single-cell and spatially resolved transcriptomics sample collection during spaceflight. Cell Reports Methods, 2(11), 100325. https://doi.org/10.1016/j.crmeth.2022.100325

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Overbey, E. G., Saravia-Butler, A. M., Zhang, Z., Rathi, K. S., Fogle, H., Barker, R. J., Bass, J. J., Beheshti, A., Berrios, D. C., Blaber, E. A., Cekanaviciute, E., Costa, H. A., Davin, L. B., Fisch, K. M., Gebre, S. G., Geniza, M., Gilbert, R., Gilroy, S., Hardiman, G., . . . Galazka, J. M. (2021). NASA GeneLab RNA-seq consensus pipeline: Standardized processing of short-read RNA-seq data. IScience, 24(4), 102361. https://doi.org/10.1016/j.isci.2021.102361

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Overbey, E. G., Da Silveira, W. A., Stanbouly, S., Nishiyama, N. C., D., G., Pecaut, M. J., Zawieja, D. C., Wang, C., Willey, J. S., Delp, M. D., Hardiman, G., & Mao, X. W. (2019). Spaceflight influences gene expression, photoreceptor integrity, and oxidative stress-related damage in the murine retina. Scientific Reports, 9(1), 1-12. https://doi.org/10.1038/s41598-019-49453-x 

 

Battle, S. L., Jayavelu, N. D., Azad, R. N., Hesson, J., Ahmed, F. N., Overbey, E. G., Zoller, J. A., Mathieu, J., Ruohola-Baker, H., Ware, C. B., & Hawkins, R. D. (2019). Enhancer Chromatin and 3D Genome Architecture Changes from Naive to Primed Human Embryonic Stem Cell States. Stem Cell Reports, 12(5), 1129. https://doi.org/10.1016/j.stemcr.2019.04.004 

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